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With an afterword by E. L. Doctorow—the novel of one man’s pursuit of intellectual freedom in the face of ignorance and corruption, from the author of Babbit Arrowsmith, the most widely read of Sinclair Lewis’s novels, is the incisive portrait of a man passionately devoted to science. As a bright, curious boy in a small Midwestern town, Martin Arrowsmith spends his free time in old Doc Vickerson’s office avidly devouring medical texts. Destined to become a physician and a researcher, he discovers that societal forces of ignorance, greed, and corruption can be as life-threatening as the plague. Part satire, part morality tale, Lewis’s novel illuminates the mystery and power of science while giving enduring life to a singular American hero’s struggle for integrity and intellectual freedom in a small-minded world. With an Introduction by Sally E. Parry and an Afterword by E. L. Doctorow