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Paul Farmer, a doctor, Harvard professor, and anthropologist, dedicated his life to diagnosing and curing infectious diseases and bringing modern medicine to those most in need. The book follows Farmer's work from Harvard to Haiti, Peru, Cuba, and Russia, as he implements his philosophy that "the only real nation is humanity" through his charity, Partners in Health. He enlists support from various organizations in his quest to cure the world, embodying a life based on hope and the understanding that problems are continuous.